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Atypical Diabetes: Pathophysiology, Clinical Presentations, and Treatment Options. Boris Draznin

Atypical Diabetes: Pathophysiology, Clinical Presentations, and Treatment Options


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ISBN: 9781580406666 | 560 pages | 14 Mb
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  • Atypical Diabetes: Pathophysiology, Clinical Presentations, and Treatment Options
  • Boris Draznin
  • Page: 560
  • Format: pdf, ePub, fb2, mobi
  • ISBN: 9781580406666
  • Publisher: American Diabetes Association
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Atypical Diabetes: Pathophysiology, Clinical Presentations, and Treatment Options by Boris Draznin Although the vast majority of diabetes cases (type 1 and type 2) are polygenic diseases, research, funded by the American Diabetes Association, has found that some forms of diabetes, distinct from type 1 or type 2 diabetes, are caused by single gene mutations. It has been estimated that these monogenic forms of diabetes account for up to five percent of all diabetes cases. In addition to monogenic diabetes, there are other atypical causes of diabetes, including: genetic defects in insulin action; diseases of the exocrine pancreas; and endocrinopathies. Given recent advances in our understanding of sub-types of diabetes, the time has come for a book on how to correctly diagnose and treat patients with atypical forms of this disorder. The book will be divided into three parts, each exploring distinct categories of atypical diabetes. Part I: Monogenic Diabetes: Genetic Defects of β-cell development and function; Part II: Insulin resistance, genetic defects in insulin action, and diseases of exocrine pancreas; Part III: Endocrinopathies, Immune-mediated diabetes, Diabetes of Unknown cause, and Other genetic syndromes sometimes associated with diabetes.

Ketosis-Prone Atypical Diabetes: Glucagon Is There, Too - NCBI - NIH
Classification of diabetes. As stated by Zimmet et al. (1) in the initial chapter of a classical textbook on diabetes, the major requirement for orderly epidemiologic, genetic, and clinical research on diabetes and glucose intolerance, and indeed for their clinical management, is an appropriate classification. Ketosis-prone atypical diabetes in Cameroonian people with
Abstract. Aim. It is unclear whether ketosis-prone diabetes is a specific type or a subtype of Type 2 diabetes. We aimed to describe the clinical and metabolicfeatures of ketosis-prone diabetes in a sub-Saharan population. Methods. We consecutively enrolled and characterized 173 people with  Diabetes Mellitus: Management of - Cleveland Clinic CME
Careful questioning about symptoms of ischemic coronary disease is still one of the most important ways to screen for CVD. Many patients with diabetes do not have typical exertional chest pain. Consequently, clinicians must ask about reduced exercise tolerance, dyspnea, or exercise-induced nausea. Various studies have  What is diabetes mellitus? (article) | Khan Academy
Diabetes can alter your body's response to certain diseases. For example, diabetics who have heart attacks are more likely to present with atypicalsymptoms (and oftentimes present without chest pain altogether). This is likely partly due to nerve damage. Many diabetics have peripheral neuropathy, a nerve condition where  What type of diabetes does my patient have and is it relevant? - AJOL
mellitus were given names descriptive of their clinical presentation. These are still in wide use even today: insulin-dependent diabetes mellitus (IDDM) and non- insulin-dependent diabetes mellitus. (NIDDM). However, as insight intopathogenesis and treatment strategies evolved, it became difficult to correctly classify  Diabetic ketoacidosis - Wikipedia
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication ofdiabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of  Ketosis-prone diabetes - Journal of Diabetes Nursing
mixed clinical picture that has features of both type 1 and type 2 diabetes. The clinical characteristics of ketosis or diabetic ketoacidosis suggest insulinopaenia at presentation, requiring intensive insulin replacement. With intensive exogenous insulin treatment, however, these people can become insulin- independent within  Approach to the patient with atypical diabetes - NCBI - NIH
Small case series and isolated case reports are common in this subject area, and we reviewed this literature, particularly for descriptions of novel therapeuticoptions. Given the emerging nature and heterogeneity of many atypical forms ofdiabetes, as well as the clinical overlap among them, the quality of the literature is  Spontaneous and long-term resolution of diabetes following diabetic
We present a case of 'atypical' diabetes and discuss its implications for diabetes professionals. Presentation. A 40-year-old Ghanaian man was admitted as an . ketoacidosis, medical practitioners do not usually entertain requests to stop insulin therapy. Atypical diabetes is probably more com- mon than is realised,  Atypical presentation of atypical mycobacteria in atypical diabetes
Other baseline biochemical parameters remained noncontributory. In view of the absence of features suggestive of Type 2 diabetes (lean built, absence of acanthosis nigricans and a family history negative for diabetes), search for an alternative etiology was pursued. An erect abdominal skiagram revealed  Atypical ketosis-prone diabetes - NCBI - NIH
The family physician made a clinical diagnosis of type 1 DM and referred her to the local diabetes management centre. She was seen the same day at thediabetes centre and started on intensive insulin therapy, with multiple daily injections, after consultation with the endocrinologist. Upon presentation her weight was 63 kg  Diabetic Neuropathy: A Position Statement by the - Diabetes Care
Screening for symptoms and signs of diabetic neuropathy is also critical inclinical practice, as it may detect the earliest stages of neuropathy, enabling early .. Despite the recent major advances in elucidating the pathogenesis of diabetic neuropathy, there remains a lack of treatment options that effectively target the  Hyperosmolar Hyperglycemic State: A Historic - Diabetes Care
Hyperosmolar Hyperglycemic State: A Historic Review of the ClinicalPresentation, Diagnosis, and Treatment .. insulin in 1922, the development ofdiabetic coma became much less frequent in patients with diabetes, and when acquired, patients had better treatment options. .. Side effects of atypical antipsychotic drugs.

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